Department of Public Health
Dr. Mohammad Mahadi Hasan  Assistant Professor
Name :
Dr. Mohammad Mahadi Hasan
Designation
Assistant Professor  
Department
Department of Public Health
Faculty
Faculty of Health and Life Sciences
Personal Webpage
https://faculty.daffodilvarsity.edu.bd/profile/ph/mahadi-ph.html
E-mail
drmahadi.ph@diu.edu.bd
Phone
Cell-Phone
PhD in Biophysical Chemistry (Mar. 2018)Department of Biophysical ChemistryKyoto Pharmaceutical University, Kyoto, Japan.
Master of Science in Biochemistry & Molecular Biology (Apr. 2014)Department of Biochemistry & Molecular BiologyRajshahi University, Bangladesh.CGPA: 3.775 out of 4, Merit Position: First Class Second.
Bachelor of Science in Biochemistry & Molecular Biology (May 2012)Department of Biochemistry & Molecular BiologyRajshahi University, Bangladesh. CGPA: 3.65 out of 4, Merit Position: First Class First.
SI No. Name of the training/Workshops/Course Date Institutions
1 Getting Published: EffectivelyCommunicating Your Research 23/03/2023-28/03/2023 Nature Research Academics, UK & Kanazawa University, Japan
2 Training on mouse embryo handling, modification and in vitro fertilization. 09/11/2022-11/11/2022 Kanazawa University, Japan
3 Course on Research Ethics 27/02/2022-02/03/2022 Kanazawa University, Japan
4 Blood born pathogen training (UHS111) 24/05/2021 University of Minnesota, USA
5 Radiation safety training (UHS301) 24/05/2021 University of Minnesota, USA
6 Introduction to research safety (UHS656) 25/05/2021 University of Minnesota, USA
7 Information security awareness training (ISA101) 25/05/2021 University of Minnesota, USA
8 Chemical safety training (UHS650) 26/05/2021 University of Minnesota, USA
9 Chemical waste management training (UHS625) 26/05/2021 University of Minnesota, USA
10 Animal use tutorial (IC1003) 27/05/2021 University of Minnesota, USA
11 Microisolator Training ((R9300) 11/06/2021 University of Minnesota, USA
12 Mouse basic and advanced handling and CO2 euthanasia training ((R1227) 15/06/2021 University of Minnesota, USA
13 Working with mice (IC3009) 18/06/2021 University of Minnesota, USA
14 Rat basic and advanced handling and CO2 euthanasia training (R2227) 29/06/2021 University of Minnesota, USA
15 Preventing sexual misconduct, discrimination and retaliation (PIPSME) 30/06/2021 University of Minnesota, USA
16 Working with Rats (IC3012) 02/07/2021 University of Minnesota, USA
17 Biological safety in the Laboratory (UHS122) 07/08/2021 University of Minnesota, USA
18 Nanomaterials lab training (MNC003) 09/07/2021 University of Minnesota, USA
19 Research Ethics Program Workshop 28/08/2019 Tokushima University, Japan
20 Basic Course on responsible conduct of research 23/07/2015-30/0720/15 Kyoto Pharmaceutical University, Japan
21 In Plant Training on Biochemistry and Cell Biology Laboratory 10/03/2012-15/03/2012 Bangladesh Institute of Health Sciences, Dhaka. Bangladesh

 

Biochemistry, Molecular Biology, Basic Chemistry, Cancer Biology

Journals: 

 

  1. Kayo Kayahashi, Mahadi Hasan, Anowara Khatun, Susumu Kohno, Jumpei Terakawa, Shin-ichi Horike, Natsumi Toyoda, Ayumi Matsuoka, Takashi Iizuka, Takeshi Obata, Masanori Ono, Yasunari Mizumoto, Chiaki Takahashi, Hiroshi Fujiwara, Takiko Daikoku. Androgen-responsive FOXP4 is a target for endometrial carcinoma. Communications Biology, 7, 740, (2024). Impact factor 5.2 (Q1)
  1. Mahadi Hasan, Anowara Khatun, Kentaro Kogure. Intradermal Delivery of Naked mRNA Vaccines via Iontophoresis. Pharmaceutics, 15(12), 2679 (2023). Impact factor 5.5 (Q1)
  1. Ara Tabassum, Ono Satoko, Mahadi Hasan, Ohzono Mizune, Kogure Kentaro. Protective effects of liposomes encapsulating ferulic acid against CCl4-induced oxidative liver damage in vivo rat model. Journal of Clinical Biochemistry and Nutrition,72 46-53, (2023). Impact factor 1.7 (Q2)
  1. Li Yue-Xuan, Wang Nianwu, Mahadi Hasan, Pang Hong-Bo. Transportan peptide enhances the cell entry of liposomes in the bystander manner. Molecular Pharmaceutics, 19, 4123-4134, (2022). Impact factor 4.5 (Q1)
  1. Mahadi Hasan, Tatsuya Fukuta, Shinya Inoue, Hinako Mori, Mayuko Kagawa, Kentaro Kogure. Iontophoresis-mediated direct delivery of nucleic acid therapeutics, without use of carriers, to internal organs via non-blood circulatory pathways. Journal of Controlled Release, 343, 392-399, (2022). Impact factor 11.5 (Q1)
  1. Mahadi Hasan, Anowara Khatun, Kentaro Kogure. Iontophoresis of biological macromolecular drugs. Pharmaceutics, 14(3), 525 (2022). Impact factor 5.5 (Q1)
  1. Anowara Khatun, Mahadi Hasan, Mahran Mohamed Abd El-Emam, Tatsuya Fukuta, Miyuki Mimura, Riho Tashima, Shintaro Yoneda, Shintaro Yoshimi, Kentaro Kogure. Effective Anticancer Therapy by Combination of Nanoparticles Encapsulating Chemotherapeutic Agents and Weak Electric Current. Biological and Pharmaceutical Bulletin, 45, 194-199, (2022). Impact factor 1.7 (Q2)
  1. Mahadi Hasan, Anowara Khatun, Tatsuya Fukuta, Kentaro Kogure. Noninvasive transdermal delivery of liposomes by weak electric current. Advanced Drug delivery Reviews, 154-155: 227-235 (2020). Impact factor 17.6 (Q1)
  1. Tasuku Torao, Miyuki Mimura, Yasufumi Oshima, Koki Fujikawa, Mahadi Hasan, Tatsuhru Shimokawa, Naoshi Yamazaki, Hidenori Ando, Tatsuhiro Ishida, Tatsuya Fukuta, Tamotsu Tanaka, Kentaro Kogure. Characteristics of unique endocytosis induced by weak current for cytoplasmic drug delivery. International Journal of Pharmaceutics, 576, 119010, (2020). Impact factor 5.2 (Q1)
  1. Mahadi Hasan, Susumu Hama, Kentaro Kogure. Low electric treatment activates Rho GTPase via heat shock protein 90 and protein kinase C for intracellular delivery of siRNA. Scientific Reports, 9, 4114 (2019). Impact factor 3.9 (Q1)
  1. Hyunkyung Jung, Yuri Shimatani, Mahadi Hasan, Kohei Uno, Susumu Hama, Kentaro Kogure. Development of flexible nanocarriers for siRNA delivery into tumor tissue. International Journal of Pharmaceutics, 516, 258-265, (2017). Impact factor 5.2 (Q1)
  1. Mahadi Hasan, Noriko Tarashima, Koki Fujikawa, Takashi Ohgita, Susumu Hama, Tamotsu Tanaka, Hiroyuki Saito, Noriaki Minakawa, Kentaro Kogure. The novel functional nucleic acid iRed effectively regulates target genes following cytoplasmic delivery by faint electric treatment. Science and Technology of Advanced Materials, 17, 554-562, (2016). Impact factor 6.9 (Q1)
  1. Mahadi Hasan, Akinori Nishimoto, Takashi Ohgita, Susumu Hama, Hiromu Kashida, Hiroyuki Asanuma, Kentaro Kogure. Faint electric treatment-induced rapid and efficient delivery of extraneous hydrophilic molecules into the cytoplasm. Journal of Controlled Release, 228, 20-25, (2016). Impact factor 11.5 (Q1)
  1. Asako Yamada, Asako Mitsueda, Mahadi Hasan, Miho Ueda, Susumu Hama, Shota Warashina, Takashi Nakamura, Hideyoshi Harashima, Kentaro Kogure. Tri-membrane nanoparticles produced by combining liposome fusion and a novel patchwork bicelles to overcome endosomal and nuclear membrane barriers to cargo delivery. Biomaterials Science, 4, 439-447, (2016). Impact factor 5.7 (Q1).
  1. MS Rahman, M Asaduzzaman, S Munira, MM Begum, MM Rahman, Mahadi Hasan, A Khatun, M Maniruzzaman, M Islam, MHK Khan, M Rahman, MR Karim, MA Islam. Comparative Study of Anti-Hyperglycemic and Anti-Hyperlipidemic Effects of Honey, Coccinia cordifolia and Hilsha Fish Oil in Streptozotocin Induced Diabetic Rats. Biology and Medicine, 8 (2), (2016).
  1. S Munira, M Asaduzzaman, Sohanur M Rahman, Muedur M Rahman, Mahadi Hasan, S Biswas, M Islam, MA Mamun, MMH Khan, MM Rahman, MR Karim, MA Islam. Evaluation of Therapeutic Efficiency of Hilsha Fish Oil on Cardiovascular Disease and Hepatic Disease Marker in Hypercholesterolemic Mice. Biology and Medicine, 7 (5), (2015).
  1. M Asaduzzaman, M Sohanur Rahman, Sirajam Munira, M Muedur Rahman, Minarul Islam, Mahadi Hasan, M Abdul Hai Siddique, Shahangir Biswas, Masudul Hasan Khan, Matiar Rahman, Mohammad Amirul Islam. Analysis of biochemical composition of honey and its anti-oxidant, Phytochemical and anti-bacterial properties. J Biomed Pharm Res. 4, (4), 69-81, (2015).
  1. Md Muedur Rahman, Mahadi Hasan, Masud Rana, Israt Ara Hossain, Md. Sohanur Rahman, Md Asaduzzaman, Sirajam Munira, Mohammad Shahangir Biswas, Mohammad Abdul Hai Siddique, Masudul Hasan Khan, Md Matiar Rahman, Md. Rezaul Karim, Liaquat Ali, Mohammad Amirul Islam. Elevated serum lipocalin-2 is a risk factor of insulin resistance and for the progression of impaired glucose to type 2 diabetes in Bangladeshi population. International Journal of Pharmacy and Technology. 7, (3), 9785-9794 (2015).
  1. M Asaduzzaman, M Sohanur Rahman, S Munira, M Muedur Rahman, Mahadi Hasan, MAH Siddique, S Biswas, MH Belal, M Khatun, MMH Khan, MM Rahman, MR Karim, AM Islam. Effects of honey supplementation on hepatic and cardiovascular disease (CVD) marker in streptozotocin-induced diabetic rats. J Diabetes Metab, 6, (592), 2 (2015).
  1. Ahsan Habib, Shahangir Biswas, Abdul Hai Siddique, Manirujjaman, Belal Uddin, Sohel Hasan, Khan MMH, Meftah Uddin, Minarul Islam, Mahadi Hasan, Muedur Rahman, Asaduzzaman M, Sohanur Rahman, Khatun M, Islam MA, Matiar Rahman. Nutritional and lipid composition analysis of pumpkin seed (Cucurbita maxima Linn.). J Nutr Food Sci. 5(4), 374, (2015).

 

 

Book Chapter:

 

  1. Mahadi Hasan. Biological Barriers for Drug Delivery to Cancer Stem Cells. In: Islam, F., Lam, A.K. (eds) Cancer Stem Cells: Basic Concept and Therapeutic Implications. 271-288, (2023) Springer. https://doi.org/10.1007/978-981-99-3185-9_15

 

Conference Abstracts, Posters, and Oral Presentations:

 

  1. Inoue Shinya, Mahadi Hasan, Fukuta Tatsuya, Kogure Kentaro. Gene expression suppression effect of siRNA delivered directly to internal organs using iontophoresis. 21st Summer Seminar of the Gene Delivery Research Society, Nagasaki, Japan,  Aug 27, 2023.
  1. Inoue Shinya, Mahadi Hasan, Fukuta Tatsuya, Kogure Kentaro. Delivery of siRNA to the liver using the transdermal drug delivery technique iontophoresis . The 39th Annual Meeting of the Japanese Society of Drug Delivery Systems, Chiba, Japan,  Jul 27-28, 2023.
  1. Kogure Kentaro, Inoue Shinya, Mahadi Hasan, Fukuta Tatsuya. Iontophoretic delivery of siRNA to internal organs. The 38th Annual Meeting of the Japanese Society of Pharmaceutical Sciences, Nagoya, Japan,  May 16-18, 2023.
  1. Inoue Shinya, Mahadi Hasan, Fukuta Tatsuya, Kogure Kentaro. Application of transdermal delivery technology iontophoresis to internal organs. The 143rd Annual Meeting of the Pharmaceutical Society of Japan, Hokkaido, Japan, Mar 25-28, 2023.
  1. Kogure Kentaro, Fukuta Tatsuya, Shinya Inoue, Mahadi Hasan. Iontophoresis-mediated direct delivery of nucleic acid therapeutics to internal organs via non-blood circulatory pathways . 7th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan, Tokyo, Japan,  July 31- Aug 3, 2022.
  1. Kogure Kentaro, Inoue Shinya, Fukuta Tatsuya, Mahadi Hasan. Iontophoretic delivery of nucleic acid drugs to the liver. The 38th Annual Meeting of the Japanese Society of Drug Delivery Systems. Webinar, Jun 29-30, 2022.
  1. Mahadi Hasan, Susumu Hama, Kentaro Kogure. Mechanistic study of low electricity mediated cytoplasmic drug delivery. APSTJ Global Education Seminar 2019, Tokushima, Japan, Jul, 2019. (Oral presentataion).
  1. Mahadi Hasan, Hama Susumu, Kogure Kentaro. Mechanistic study of faint electric treatment mediated cytoplasmic delivery of siRNA . 40th Symposium on Biomembrane-Drug Interactions, Sendai, Japan, 18-19, 2018. (Oral presentataion)
  1. Tanaka Daichi, Mahadi Hasan, Fukuta Tatsuya, Tanaka Tamotsu, Kogure Kentaro. Intrarenal delivery of nucleic acid drugs by iontophoresis for the treatment of kidney diseases . The 33rd Annual Meeting of the Japanese Society of Pharmaceutical Sciences, Shizuoka, Japan, May 30, 2018.
  1. Mahadi Hasan, Susumu Hama, Saito Hiroyuki, Kogure Kogure. Mechanistic analysis of the intracellular delivery of siRNA mediated by faint electric treatment. 138th Annual Meeting of the Pharmaceutical Society of Japan, Kanazawa, Japan, Mar 25-28, 2018. (Oral presentataion)
  1. Yasushi Ohshima, Mahadi Hasan, Noriko Tarashima, Susumu Hama, Tatsuya Fukuta, Tamotsu Tanaka, Noriaki Minakawa, Kentaro Kogure. Intracellular uptake of functional nucleic acids using weak current treatment . 138th Annual Meeting of the Pharmaceutical Society of Japan, Kanazawa, Japan, Mar 25-28, 2018.
  1. Yasushi Ohshima, Yu Torao, Miyuki Mimura, Mahadi Hasan, Noriko Tarashima, Susumu Hama, Tatsuya Fukuta, Tamotsu Tanaka, Noriaki Minakawa, Kentaro Kogure. Cytoplasmic delivery of functional nucleic acids using a unique endocytosis-inducing weak electric current . The 56th Annual Meeting of the Pharmaceutical Society of Japan, the Japan Pharmaceutical Association, and the Japanese Society of Hospital Pharmacists, Chugoku-Shikoku Branch, Tokushima, Japan, Oct 21-22, 2017.
  1. Yasushi Ohshima, Torao Tasuku, Miyuki Mimura, Takaki Fujikawa, Mahadi Hasan, Susumu Hama, Tamotsu Tanaka, Kentaro Kogure. Analysis of a unique endocytosis induced by weak electric current. 17th Symposium of the Gene Delivery Research Society, Osaka, Japan, May 17, 2017.
  1. Kogure Kentaro; Tarashima Noriko,Torao Tasuku, Mahadi Hasan, Susumu Hama, Tamotsu Tanaka, Hiroyuki Saito, Minakawa Noriaki. Effective cellular delivery of intelligent shRNA expression device by faint electricity. 6th FIP Pharmaceutical Sciences World Congress (PSWC), Stockholm, Sweden, May 21-24, 2017.
  1. Kentaro Kogure, Mahadi Hasan, Noriko Tarashima, Kohki Fujikawa, Susumu Hama, Tamotsu Tanaka, Kei Kashida, Hiroyuki Asanuma, Hiroyuki Saito, Noriaki Minakawa. Efficient cytoplasmic delivery of functional nucleic acids by weak electric current. The 2nd Annual Meeting of the Japanese Society for Nucleic Acid Medicine, Tokyo, Japan, Nov 15-17, 2016.
  1. Fujikawa Kohki, Mahadi Hasan, Hama Susumu, Tanaka Tamotsu, Saito Hiroyuki, Kogure Kentaro. Cytoplasmic delivery of macromolecular substances by weak electric current treatment. The 38th Symposium on Biomembrane-Drug Interactions, Nagoya, Japan, Nov 18, 2016.
  1. Fujikawa Kohki, Mahadi Hasan, Hama Susumu, Tanaka Tamotsu, Kogure Kentaro. Faint electric treatment induces cytoplasmic delivery of functional macromolecules via changing endosome property. 3rd International Conference on Biomaterials Science in Tokyo (ICBS2016) (Tokyo, Japan), Nov 28-30, 2016.
  1. Kohki Fujikawa, Mahadi Hasan, Susumu Hama, Tamotsu Tanaka, Kentaro Kogure. Weak electric current treatment induces changes in endosomal properties in cells. The 55th Academic Conference of the Pharmaceutical Society of Japan, the Japan Pharmaceutical Association, and the Japanese Society of Hospital Pharmacists, Chugoku-Shikoku Branch, Okayama, Japan, Nov 5-6, 2016.
  1. Mahadi Hasan, Noriko Tarashima, Kohki Fujikawa, Takashi Ohgita, Susumu Hama, Tamotsu Tanaka, Hiroyuki Saito, Noriaki Minakawa, Kentaro Kogure. Intracellular delivery of a novel functional nucleic acid iRed by faint electric treatment for effective regulation of target genes. The 32nd DDS Academic Conference, Sizuoka, Japan,  June 30-July 1, 2016. (Poster presentation)
  1. Kohki Fujikawa, Mahadi Hasan, Susumu Hama, Tamotsu Tanaka, Kentaro Kogure. Analysis of endocytosis induced by weak electric current treatment. The 31st Annual Meeting of the Japanese Society of Pharmaceutical Sciences. Gifu, Japan, May 19-21, 2016.
  1. Mahadi Hasan, Akinori Nishimoto, Takashi Ohgita, Susumu Hama, Kentaro Kogure. Faint electric treatment enhances cellular uptake and intracellular delivery into cytoplasm. The 136th Annual Meeting of the Japanese Society of Pharmaceutical Sciences, Yokohama, Japan, Mar 26-29, 2016. (Oral presentataion)
  1. Mahadi Hasan, Akinori Nishimoto, Takashi Ohgita, Susumu Hama, Kentaro Kogure. Mechanistic study of cytoplasmic drug delivery by faint electricity. 1st Annual meeting of the Nucleic Acid Therapeutic Society of Japan, Kyoto, Japan, Nov 30 -Dec 02, 2015. (Poster presentation).
  1. A novel mechanism of menopause-induced endometrial cancer that develops through functional loss of the helicase family, Grant-in-Aid for Early-Career Scientists (24K19688), Japan Society for the Promotion of Science (JSPS), April 2024 - March 2026, Mahadi Hasan (Granted amount 4.68 million JPY).
  1. A new mechanism for acquiring cancer immunity tolerance for cancer cells that evolve via cell fusion with host immune cells. Grant-in-Aid for Challenging Research (Exploratory) (24K22161), Japan Society for the Promotion of Science (JSPS), June 2024 - Mar 2026, Takiko Daikoku, Mahadi Hasan, Kagami Kyosuke (Granted amount 6.5 million JPY).
  1. Development of pinpoint genome editing technology at specific organ for the treatment of fatal diseases via low electricity. Tokyo Biochemical Research Foundation (TBRF) grant for Asian Researcher FY2020-21, Mahadi Hasan, Kentaro Kogure (Granted amount 3 million JPY).
  2.  Confirmation of the molecular mechanism of cytoplasmic drug delivery via faint electricity.
  1. Tokyo Biochemical Research Foundation (TBRF) Postdoctoral Fellowship for Asian Researcher FY2020-21, Japan.
  2. The Academy of Pharmaceutical Science and Technology Global Education Seminar Presentation Award 2019, Japan.
  3. Japan Society for the Promotion of Science (JSPS) Postdoctoral Research Fellowship (standard) FY2018 Japan.
  4. Tokyo Biochemical Research Foundation (TBRF) Scholarship for Graduate Student 2015, Japan.
  5. Kyoto Pharmaceutical University Scholarship for Graduate Student 2015, Japan.
Assistant ProfessorResearch Center for Experimental Modeling of Human Disease, Kanazawa University, Japan. (Dec. 2021 – Dec. 2025)
Postdoctoral Research AssociateDepartment of Pharmaceutics, School of Pharmacy, University of Minnesota, USA. (May 2021 – Nov. 2021).
Tokyo Biochemical Research Foundation (TBRF) Postdoctoral FellowDepartment of Pharmaceutical Health Chemistry,Graduate School of Biomedical Sciences, Tokushima University, Japan. (Apr. 2020 – Apr. 2021).
Japan Society for the Promotion of Science (JSPS) Postdoctoral FellowDepartment of Pharmaceutical Health Chemistry,Graduate School of Biomedical Sciences, Tokushima University,Japan. (Apr. 2018 – Mar. 2020). 
Research Assistant Department of Biophysical Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan. (Apr. 2015 – Mar. 2018)
Research TraineeDepartment of Biophysical Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan. (Nov. 2014 – Mar. 2015)