Department of Pharmacy
Dr. Md. Shafikur Rahman  Associate Professor
Name :
Dr. Md. Shafikur Rahman
Employee ID
710003721
Designation
Associate Professor  
Department
Department of Pharmacy
Faculty
Faculty of Health and Life Sciences
Personal Webpage
https://faculty.daffodilvarsity.edu.bd/profile/pharmacy/drshafikur.html
E-mail
rahman.pharm@diu.edu.bd
Phone
Cell-Phone
01304780185
  • Ph.D. (University of Nebraska, USA)
  • Post-doctorate (University of Wisconsin, USA)
  • PGD (Texas Tech University, USA)
  • B. Pharm. (Hons.), M. Pharm. (University of Dhaka)

 

Medicinal Chemistry, Organic Synthesis, Drug Design and Discovery, Chemical Biology, Pharmacokinetics, Pharmacodynamics, Experimental Design, Handling of Radiochemicals, Laboratory Safety, Cell Culture, Western Blotting, Protein Expression and Quantification, Gel Electrophoresis, NMR, LC-MS (HRMS, LRMS), Microwave Reactor, Flash Column Chromatography, HPLC, Polarimetry, FT-IR, UV-Vis Spectrophotometry, Molecular Modeling, Structure-Based Drug Design, etc. Transferable skills: Presentation of Medicinal Chemistry concepts, strategic synthesis planning, and collaboration, Research Ethics, Teaching Methodology.

  • Medicinal Chemistry
  • Organic Chemistry
  • Analytical Chemistry
  • Pharmacology
  • Biochemistry
  • Physiology

 

Journal Articles

 

  • Rahman, S.; Esfahani, S.H.; Zhang, Y.; Queen, A.; Aljarrah, M.; Kandil, H.; Baez, A.; Abbruscato, T.J.; Karamyan, V.T.; Trippier, P.C. Imidazole bioisostere activators of endopeptidase neurolysin with enhanced potency and metabolic stability. ACS Med. Chem. Lett. 2024,15, 510-517.
  • Rahman, M.S.; Esfahani, S.H.; Nozohouri, S.; Kumari, S.; Kocot, J.; Yong Z.; Abbruscato, T.J.; Karamyan, V.T.; Trippier, P.C. Structure-activity relationship studies of functionalized aromatic peptidomimetics as neurolysin Bioorg. Med. Chem. Lett. 2022, 64, 128669.
  • Nozohouri, ; Esfahani, S.H.; Noorani, B.; Patel, D.; Villalba H.; Ghanwatkar, Y.; Rahman, M. S.; Zhang, Y.; Karamyan, V.T.; Trippier, P.C.; Abbruscato, T.J.; In-Vivo and ex-vivo brain uptake studies of peptidomimetic neurolysin activators in healthy and stroke animals. Pharm. Res. 2022, 39 (7), 1587-1598.
  • Rahman, S.; Kumari, S.; Esfahani, S. H.; Nozohouri, S.; Jayaraman, S.; Kinarivala, N.; Kocot, J.; Baez, A.; Farris, D.; Abbruscato, T. J.; Karamyan, V. T.; Trippier, P. C., Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability. J. Med. Chem. 2021, 64 (17), 12705-12722.
  • Rahman, M. S., Moly, N. N. and Hossen, M. J. Antimicrobial, cytotoxic and antioxidant activity of the exudates of Calotropis gigantea. J. Pharm. Sci. and Res.2013,4(2),745-753.
  • Rahman, M.S., Sultana, S. Antimicrobial, antioxidant, and cytotoxic effects of the bark of Terminalia arjuna. J. Pharm. Sci. and Res. 2012, 3(1), 130-137.
  • Rahman, S., Shams-Ud-Doha, K. M., & Rahman, R. Antidiarrheal activity of the leaf and fruit extracts of Dillenia indica. Int. J. of Biosci. 2011,1(6), 39– 46.
  • Rahman, S., Akbor, M.M., Howlader, A. and Jabbar, A. Antimicrobial and cytotoxic activity of the alkaloids of Amlaki (Emblica officinalis). Pak. J. Bio. Sci. 2009,12,1152-1155.
  • Ahmed, F., Rahman, S., Sarkar, M.R. Antidiarrheal, Antidiabetic, Antibacterial and Antioxidant Activity of methanolic extracts from leaves of Clerodendrum viscosum, Paperback, 52 Pages, Lap Lambert Academic Publishing.2012, ISBN-13: 978-3-659-21149- 2, ISBN: 3-659-21149-4

 

Conference Papers

 

  • ’Synthesis and Evaluation of Peptidase Neurolysin (Nln) Activators to treat Ischemic Stroke’ Presented in the Ninth Structural Biology and Molecular Biophysical Workshop at the University of Nebraska Medical Center, USA, 2022.
  • ’Synthesis and Evaluation of Peptidase Neurolysin (Nln) Activators to treat Ischemic Stroke’ Presented in the American Chemical Society (ACS) National Meeting, Chicago, Illinois, USA, Fall, 2022.
  • ’Synthesis and Evaluation of Novel Peptidomimetics as Selective Neurolysin Activators for the Potential Treatment of Ischemic Stroke’ Presented in the Pharmaceutical Sciences Departmental Seminar at the University of Nebraska Medical Center, USA, September 30, 2022.
  • ’Synthesis and Evaluation of Novel Peptidomimetics as Selective Neurolysin Activators for the Potential Treatment of Ischemic Stroke’ Presented on the Research Day, College of Pharmacy, University of Nebraska Medical Center, USA, May 23, 2023.
  • ’Synthesis and Evaluation of Novel Peptidomimetics as Selective Neurolysin Activators for the Potential Treatment of Ischemic Stroke’ Presented in the 54th Annual Midwest Student Biomedical Research Forum at Creighton University, Omaha, USA, March 4, 2023.
  • ’Synthesis and Evaluation of Novel Peptidomimetics as Selective Neurolysin Activators for the Potential Treatment of Ischemic Stroke’ Presented in the Chemistry Departmental Seminar at the University of Nebraska Omaha, USA, February 13, 2023.

Drug Design and Discovery through Organic Synthesis and Medicinal Chemistry

  • Program of Excellence Award from the University of Nebraska Medical Center, USA for Research and Academic Excellence worth USD 56000.00
  • Scholarship from the University of Nebraska Medical Center, USA for PhD research worth USD 105000.00.
  • Scholarship from Texas Tech University, USA for PhD research worth USD 125000.00.
  • Scholarship from Bangladesh Education Board for outstanding result on HSC.
  • American Chemical Society (ACS) Local Section Coordinator, Wisconsin for the US National Chemistry Olympiad (USNCO), USA. 2023-2024
  • Member, American Chemical Society (ACS), USA. 2022-2024
  • Member, Post-Doctoral Association, University of Wisconsin-Madison, USA. 2023-2024
  • Member, Graduate Student Senate, University of Nebraska Medical Center, USA. 2021-2022
  • Member, Graduate Student Association (GSA), University of Nebraska Medical Center, USA. 2019-2023
  • Member, Graduate Student Association (GSA), Texas Tech University Health Sciences Center, USA. 2018-2019
  1. Postdoctoral Research Associate (University of Wisconsin Madison, USA (September 01, 2023 – June 14, 2024)
  2. Graduate Research Assistant, University Nebraska Medical Center, USA (August 10, 2019 – July 21, 2023)
  3. Graduate Research Assistant, Texas Tech University Health Sciences Center, USA (August 04, 2018 – August 01, 2019)
  4. Graduate Teaching Assistant, Texas Tech University Health Sciences Center, USA (August 04, 2018 – August 01, 2019)
  5. Superintendent of Drugs, DGDA, Ministry of Health, Bangladesh (February 27, 2013 – July 30, 2018)
  6. Faculty Member, Pharmacy Department, Southeast University, (July 07, 2007- April 01, 2013)
  7. Product Executive, ACI Pharma. Ltd. (April 04, 2006- Mach 30, 2007)
  8. Product Development Executive, Somatec Pharma. Ltd. (January 18, 2006- April 01, 2006)